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Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App(NL−G−F) knock-in Alzheimer mice
BACKGROUND: Alzheimer’s disease (AD) is an age-related disease characterized by altered cognition, neuroinflammation, and neurodegeneration against which there is presently no effective cure. Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in the learning and memory process,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436657/ https://www.ncbi.nlm.nih.gov/pubmed/37596686 http://dx.doi.org/10.1186/s13195-023-01282-x |