Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis

BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), accelerated aging of the immune system (immunosenescence) may be associated with disease onset or drive progression. DNA methylation (DNAm) is an epigenetic factor that varies among lymphocyte subtypes, and cell-specific DNAm is associated with...

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Detalles Bibliográficos
Autores principales: Maltby, Vicki, Xavier, Alexandre, Ewing, Ewoud, Campagna, Maria-Pia, Sampangi, Sandeep, Scott, Rodney J., Butzkueven, Helmut, Jokubaitis, Vilija, Kular, Lara, Bos, Steffan, Slee, Mark, van der Mei, Ingrid A., Taylor, Bruce V., Ponsonby, Anne-Louise, Jagodic, Maja, Lea, Rodney, Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437016/
https://www.ncbi.nlm.nih.gov/pubmed/37541839
http://dx.doi.org/10.1212/WNL.0000000000207489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437016/
https://www.ncbi.nlm.nih.gov/pubmed/37541839
http://dx.doi.org/10.1212/WNL.0000000000207489

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