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Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), accelerated aging of the immune system (immunosenescence) may be associated with disease onset or drive progression. DNA methylation (DNAm) is an epigenetic factor that varies among lymphocyte subtypes, and cell-specific DNAm is associated with...
Autores principales: | Maltby, Vicki, Xavier, Alexandre, Ewing, Ewoud, Campagna, Maria-Pia, Sampangi, Sandeep, Scott, Rodney J., Butzkueven, Helmut, Jokubaitis, Vilija, Kular, Lara, Bos, Steffan, Slee, Mark, van der Mei, Ingrid A., Taylor, Bruce V., Ponsonby, Anne-Louise, Jagodic, Maja, Lea, Rodney, Lechner-Scott, Jeannette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437016/ https://www.ncbi.nlm.nih.gov/pubmed/37541839 http://dx.doi.org/10.1212/WNL.0000000000207489 |
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