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Deletion of the non-adjacent genes UL148 and UL148D impairs human cytomegalovirus-mediated TNF receptor 2 surface upregulation

Human cytomegalovirus (HCMV) is a prototypical β-herpesvirus which frequently causes morbidity and mortality in individuals with immature, suppressed, or senescent immunity. HCMV is sensed by various pattern recognition receptors, leading to the secretion of pro-inflammatory cytokines including tumo...

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Detalles Bibliográficos
Autores principales: Le-Trilling, Vu Thuy Khanh, Maaßen, Fabienne, Katschinski, Benjamin, Hengel, Hartmut, Trilling, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437809/
https://www.ncbi.nlm.nih.gov/pubmed/37600801
http://dx.doi.org/10.3389/fimmu.2023.1170300