Uncovering the phenotypic consequences of multi-locus imprinting disturbances using genome-wide methylation analysis in genomic imprinting disorders

Imprinted genes are regulated by DNA methylation of imprinted differentially methylated regions (iDMRs). An increasing number of patients with congenital imprinting disorders (IDs) exhibit aberrant methylation at multiple imprinted loci, multi-locus imprinting disturbance (MLID). We examined MLID an...

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Detalles Bibliográficos
Autores principales: Kim, Hwa Young, Shin, Choong Ho, Shin, Chang Ho, Ko, Jung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437897/
https://www.ncbi.nlm.nih.gov/pubmed/37594968
http://dx.doi.org/10.1371/journal.pone.0290450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437897/
https://www.ncbi.nlm.nih.gov/pubmed/37594968
http://dx.doi.org/10.1371/journal.pone.0290450

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