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New Strategies in Controlling Drug Resistance

BACKGROUND: Chronic myeloid leukemia (CML) is most often caused by the translocation of chromosomes 9 and 22 to create the fusion protein, BCR-ABL. This constitutively active tyrosine kinase promotes cell division and blocks apoptosis, leading to unregulated growth of hematopoietic stem cells. Imati...

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Detalles Bibliográficos
Autor principal: Frame, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Managed Care Pharmacy 2007
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437929/
https://www.ncbi.nlm.nih.gov/pubmed/17970610
http://dx.doi.org/10.18553/jmcp.2007.13.s8-a.13