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New Strategies in Controlling Drug Resistance
BACKGROUND: Chronic myeloid leukemia (CML) is most often caused by the translocation of chromosomes 9 and 22 to create the fusion protein, BCR-ABL. This constitutively active tyrosine kinase promotes cell division and blocks apoptosis, leading to unregulated growth of hematopoietic stem cells. Imati...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academy of Managed Care Pharmacy
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437929/ https://www.ncbi.nlm.nih.gov/pubmed/17970610 http://dx.doi.org/10.18553/jmcp.2007.13.s8-a.13 |