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Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Lipid nanoparticles (LNPs) are a potent delivery technology that have made it possible for the recent clinical breakthroughs in mRNA therapeutics and vaccines. A key challenge to the broader implementation of mRNA therapeutics and vaccines is the development of technology to produce precisely define...

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Detalles Bibliográficos
Autores principales: Shepherd, Sarah J., Han, Xuexiang, Mukalel, Alvin J., El-Mayta, Rakan, Thatte, Ajay S., Wu, Jingyu, Padilla, Marshall S., Alameh, Mohamad-Gabriel, Srikumar, Neha, Lee, Daeyeon, Weissman, Drew, Issadore, David, Mitchell, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438381/
https://www.ncbi.nlm.nih.gov/pubmed/37556502
http://dx.doi.org/10.1073/pnas.2303567120