An iron–sulfur cluster in the zinc-binding domain of the SARS-CoV-2 helicase modulates its RNA-binding and -unwinding activities

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, uses an RNA-dependent RNA polymerase along with several accessory factors to replicate its genome and transcribe its genes. Nonstructural protein (nsp) 13 is a helicase required for viral replication. Here...

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Detalles Bibliográficos
Autores principales: Maio, Nunziata, Raza, Md Kausar, Li, Yan, Zhang, De-Liang, Bollinger, J. Martin, Krebs, Carsten, Rouault, Tracey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438387/
https://www.ncbi.nlm.nih.gov/pubmed/37552760
http://dx.doi.org/10.1073/pnas.2303860120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438387/
https://www.ncbi.nlm.nih.gov/pubmed/37552760
http://dx.doi.org/10.1073/pnas.2303860120

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