Cultivated autologous limbal epithelial cell (CALEC) transplantation: Development of manufacturing process and clinical evaluation of feasibility and safety

To treat unilateral limbal stem cell (LSC) deficiency, we developed cultivated autologous limbal epithelial cells (CALEC) using an innovative xenobiotic-free, serum-free, antibiotic-free, two-step manufacturing process for LSC isolation and expansion onto human amniotic membrane with rigorous qualit...

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Detalles Bibliográficos
Autores principales: Jurkunas, Ula V., Yin, Jia, Johns, Lynette K., Li, Sanming, Negre, Helene, Shaw, Kit L., Samarakoon, Lassana, Ayala, Allison R., Kheirkhah, Ahmad, Katikireddy, Kishore, Gauthier, Alex, Ong Tone, Stephan, Kaufman, Aaron R., Ellender, Stacey, Hernandez Rodriguez, Diego E., Daley, Heather, Dana, Reza, Armant, Myriam, Ritz, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438443/
https://www.ncbi.nlm.nih.gov/pubmed/37595035
http://dx.doi.org/10.1126/sciadv.adg6470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438443/
https://www.ncbi.nlm.nih.gov/pubmed/37595035
http://dx.doi.org/10.1126/sciadv.adg6470

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