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Impaired thymic iNKT cell differentiation at early precursor stage in murine haploidentical bone marrow transplantation with GvHD

INTRODUCTION: Early recovery of donor-derived invariant natural killer T (iNKT) cells are associated with reduced risk of graft-versus-host disease (GvHD) and overall survival. Patients with severe GvHD, however, had much slower iNKT cell reconstitution relative to conventional T cells. METHODS: To...

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Detalles Bibliográficos
Autores principales: Zhao, Weijia, Wang, Yujia, Zhang, Xinwei, Hao, Jie, Zhang, Kunshan, Huang, Xiaojun, Chang, Yingjun, Wu, Hounan, Jin, Rong, Ge, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438461/
https://www.ncbi.nlm.nih.gov/pubmed/37600815
http://dx.doi.org/10.3389/fimmu.2023.1203614