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TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain

Immunological control of viral infections in the brain exerts immediate protection and also long-term maintenance of brain integrity. Microglia are important for antiviral defense in the brain. Here, we report that herpes simplex virus type 1 (HSV1) infection of human induced pluripotent stem cell (...

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Detalles Bibliográficos
Autores principales: Fruhwürth, Stefanie, Reinert, Line S., Öberg, Carl, Sakr, Marcelina, Henricsson, Marcus, Zetterberg, Henrik, Paludan, Søren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438464/
https://www.ncbi.nlm.nih.gov/pubmed/37595041
http://dx.doi.org/10.1126/sciadv.adf5808