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Acylated- and unacylated ghrelin during an oral glucose tolerance test in humans at risk for type 2 diabetes mellitus

BACKGROUND/OBJECTIVES: The orexigenic peptide hormone ghrelin has been implicated in the pathophysiology of obesity and type 2 diabetes mellitus through its effects on nutrient homeostasis. Ghrelin is subject to a unique post-translational acyl modification regulating its biochemical activity. SUBJE...

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Detalles Bibliográficos
Autores principales: Wolf, Magnus, Heni, Martin, Hennige, Anita M., Sippel, Katrin, Cegan, Alexander, Higuita, Lina María Serna, Martus, Peter, Häring, Hans-Ulrich, Fritsche, Andreas, Peter, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439001/
https://www.ncbi.nlm.nih.gov/pubmed/37420007
http://dx.doi.org/10.1038/s41366-023-01327-z