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Exploitation of ATP-sensitive potassium ion (K(ATP)) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

Persistent infection with high-risk human papillomaviruses (HPVs) is the causal factor in multiple human malignancies, including >99% of cervical cancers and a growing proportion of oropharyngeal cancers. Prolonged expression of the viral oncoproteins E6 and E7 is necessary for transformation to...

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Detalles Bibliográficos
Autores principales: Scarth, James A., Wasson, Christopher W., Patterson, Molly R., Evans, Debra, Barba-Moreno, Diego, Carden, Holli, Cassidy, Rosa, Whitehouse, Adrian, Mankouri, Jamel, Samson, Adel, Morgan, Ethan L., Macdonald, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439009/
https://www.ncbi.nlm.nih.gov/pubmed/37443304
http://dx.doi.org/10.1038/s41388-023-02772-w