Early-adulthood spike in protein translation drives aging via juvenile hormone/germline signaling

Protein translation (PT) declines with age in invertebrates, rodents, and humans. It has been assumed that elevated PT at young ages is beneficial to health and PT ends up dropping as a passive byproduct of aging. In Drosophila, we show that a transient elevation in PT during early-adulthood exerts...

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Detalles Bibliográficos
Autores principales: Kim, Harper S., Parker, Danitra J., Hardiman, Madison M., Munkácsy, Erin, Jiang, Nisi, Rogers, Aric N., Bai, Yidong, Brent, Colin, Mobley, James A., Austad, Steven N., Pickering, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439225/
https://www.ncbi.nlm.nih.gov/pubmed/37596266
http://dx.doi.org/10.1038/s41467-023-40618-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439225/
https://www.ncbi.nlm.nih.gov/pubmed/37596266
http://dx.doi.org/10.1038/s41467-023-40618-x

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