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Early-adulthood spike in protein translation drives aging via juvenile hormone/germline signaling
Protein translation (PT) declines with age in invertebrates, rodents, and humans. It has been assumed that elevated PT at young ages is beneficial to health and PT ends up dropping as a passive byproduct of aging. In Drosophila, we show that a transient elevation in PT during early-adulthood exerts...
Autores principales: | Kim, Harper S., Parker, Danitra J., Hardiman, Madison M., Munkácsy, Erin, Jiang, Nisi, Rogers, Aric N., Bai, Yidong, Brent, Colin, Mobley, James A., Austad, Steven N., Pickering, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439225/ https://www.ncbi.nlm.nih.gov/pubmed/37596266 http://dx.doi.org/10.1038/s41467-023-40618-x |
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