The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation

Anticopalic acid (ACP), a labdane type diterpenoid obtained from Kaempferia elegans rhizomes, together with 21 semi-synthetic derivatives, were evaluated for their cancer cytotoxic activity. Most derivatives displayed higher cytotoxic activity than the parent compound ACP in a panel of nine cancer c...

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Detalles Bibliográficos
Autores principales: Chawengrum, Pornsuda, Luepongpatthana, Natthaorn, Thongnest, Sanit, Sirirak, Jitnapa, Boonsombat, Jutatip, Lirdprapamongkol, Kriengsak, Keeratichamroen, Siriporn, Kongwaen, Patcharin, Montatip, Phreeranat, Kittakoop, Prasat, Svasti, Jisnuson, Ruchirawat, Somsak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439230/
https://www.ncbi.nlm.nih.gov/pubmed/37596365
http://dx.doi.org/10.1038/s41598-023-40669-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439230/
https://www.ncbi.nlm.nih.gov/pubmed/37596365
http://dx.doi.org/10.1038/s41598-023-40669-6

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