Cargando…
The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation
Anticopalic acid (ACP), a labdane type diterpenoid obtained from Kaempferia elegans rhizomes, together with 21 semi-synthetic derivatives, were evaluated for their cancer cytotoxic activity. Most derivatives displayed higher cytotoxic activity than the parent compound ACP in a panel of nine cancer c...
Autores principales: | Chawengrum, Pornsuda, Luepongpatthana, Natthaorn, Thongnest, Sanit, Sirirak, Jitnapa, Boonsombat, Jutatip, Lirdprapamongkol, Kriengsak, Keeratichamroen, Siriporn, Kongwaen, Patcharin, Montatip, Phreeranat, Kittakoop, Prasat, Svasti, Jisnuson, Ruchirawat, Somsak |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439230/ https://www.ncbi.nlm.nih.gov/pubmed/37596365 http://dx.doi.org/10.1038/s41598-023-40669-6 |
Ejemplares similares
-
JAK2/STAT3-mediated dose-dependent cytostatic and cytotoxic effects of sesquiterpene lactones from Gymnanthemum extensum on A549 human lung carcinoma cells
por: Keeratichamroen, Siriporn, et al.
Publicado: (2022) -
Kaemtakols A–D, highly oxidized pimarane diterpenoids with potent anti-inflammatory activity from Kaempferia takensis
por: Jongsomjainuk, Orawan, et al.
Publicado: (2023) -
Novel psoralen derivatives as anti-breast cancer agents and their light-activated cytotoxicity against HER2 positive breast cancer cells
por: Aekrungrueangkit, Chiphada, et al.
Publicado: (2022) -
An anticonvulsive drug, valproic acid (valproate), has effects on the biosynthesis of fatty acids and polyketides in microorganisms
por: Poolchanuan, Prapassorn, et al.
Publicado: (2020) -
Drimane Sesquiterpene-Conjugated Amino Acids from a Marine Isolate of the Fungus Talaromyces minioluteus (Penicillium Minioluteum)
por: Ngokpol, Suthatip, et al.
Publicado: (2015)