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Serotonin secretion by blood platelets: accuracy of high-performance liquid chromatography-electrochemical technique compared with the isotopic test and use in a clinical laboratory

BACKGROUND: Mild secretion defects are the most frequent and challenging blood platelet disorders to diagnose. Most δ-granule secretion tests lack validation, are not quantitative, or have unreliable response to weak platelet agonists. OBJECTIVES: To compare platelet serotonin secretion by HPLC-elec...

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Detalles Bibliográficos
Autores principales: Aranda, Eduardo, Iha, Seiki, Solari, Sandra, Rodríguez, David, Romero, Viviana, Villarroel, Luis, Pereira, Jaime, Panes, Olga, Mezzano, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439442/
https://www.ncbi.nlm.nih.gov/pubmed/37601022
http://dx.doi.org/10.1016/j.rpth.2023.102156