Fibrinogen BOE II: dysfibrinogenemia with bleeding and defective thrombin binding

BACKGROUND: Variants of fibrinogen sequences that bind to thrombin’s catalytic sites are mostly associated with bleeding phenotypes, while variants with fibrinogen nonsubstrate-thrombin–binding sites are commonly believed to cause thrombosis. AαGlu39 and BβAla68 play important roles in fibrin(ogen)-...

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Detalles Bibliográficos
Autores principales: Li, Yang, Liang, Qian, Wu, Wenman, Hu, Xiaobo, Wang, Hualiang, Wang, Xuefeng, Ding, Qiulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439445/
https://www.ncbi.nlm.nih.gov/pubmed/37601017
http://dx.doi.org/10.1016/j.rpth.2023.102145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439445/
https://www.ncbi.nlm.nih.gov/pubmed/37601017
http://dx.doi.org/10.1016/j.rpth.2023.102145

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