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Fibrinogen BOE II: dysfibrinogenemia with bleeding and defective thrombin binding
BACKGROUND: Variants of fibrinogen sequences that bind to thrombin’s catalytic sites are mostly associated with bleeding phenotypes, while variants with fibrinogen nonsubstrate-thrombin–binding sites are commonly believed to cause thrombosis. AαGlu39 and BβAla68 play important roles in fibrin(ogen)-...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439445/ https://www.ncbi.nlm.nih.gov/pubmed/37601017 http://dx.doi.org/10.1016/j.rpth.2023.102145 |