Cargando…

Combination therapies for the optimisation of Bispecific T-cell Engagers in cancer treatment

Bispecific T-cell engagers (BiTEs) redirect endogenous T-cell populations to cells expressing tumour-associated antigens to induce tumour cell killing. This inherently relies upon a cytotoxic T-cell population that is able to be recruited. In many cancers, immune checkpoints and other immunosuppress...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Winston M, Middleton, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439528/
https://www.ncbi.nlm.nih.gov/pubmed/37599903
http://dx.doi.org/10.1093/immadv/ltad013