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Combination therapies for the optimisation of Bispecific T-cell Engagers in cancer treatment
Bispecific T-cell engagers (BiTEs) redirect endogenous T-cell populations to cells expressing tumour-associated antigens to induce tumour cell killing. This inherently relies upon a cytotoxic T-cell population that is able to be recruited. In many cancers, immune checkpoints and other immunosuppress...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439528/ https://www.ncbi.nlm.nih.gov/pubmed/37599903 http://dx.doi.org/10.1093/immadv/ltad013 |