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Paternal high-fat diet altered SETD2 gene methylation in sperm of F0 and F1 mice

Paternal high-fat diet (HFD) can alter the epigenetics of sperm DNA, resulting in the transmission of obesity-related traits to the offspring. Previous studies have mainly focused on the HFD-induced changes in DNA methylation of imprinted genes, overlooking the potential involvement of non-imprinted...

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Detalles Bibliográficos
Autores principales: Wei, Suhua, Luo, Shiwei, Zhang, Haifeng, Li, Yandong, Zhao, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439541/
https://www.ncbi.nlm.nih.gov/pubmed/37598138
http://dx.doi.org/10.1186/s12263-023-00731-4