rBahadur: efficient simulation of structured high-dimensional genotype data with applications to assortative mating

Existing methods for generating synthetic genotype data are ill-suited for replicating the effects of assortative mating (AM). We propose rb_dplr, a novel and computationally efficient algorithm for generating high-dimensional binary random variates that effectively recapitulates AM-induced genetic...

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Detalles Bibliográficos
Autores principales: Border, Richard, Malik, Osman Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439545/
https://www.ncbi.nlm.nih.gov/pubmed/37596553
http://dx.doi.org/10.1186/s12859-023-05442-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439545/
https://www.ncbi.nlm.nih.gov/pubmed/37596553
http://dx.doi.org/10.1186/s12859-023-05442-6

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