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rBahadur: efficient simulation of structured high-dimensional genotype data with applications to assortative mating
Existing methods for generating synthetic genotype data are ill-suited for replicating the effects of assortative mating (AM). We propose rb_dplr, a novel and computationally efficient algorithm for generating high-dimensional binary random variates that effectively recapitulates AM-induced genetic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439545/ https://www.ncbi.nlm.nih.gov/pubmed/37596553 http://dx.doi.org/10.1186/s12859-023-05442-6 |