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Association between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort

BACKGROUND: Acetaminophen is a commonly used medication by pregnant women and is known to cross the placenta. However, little is known about the biological mechanisms that regulate acetaminophen in the developing offspring. Cytochrome 2E1 (CYP2E1) is the primary enzyme responsible for the conversion...

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Detalles Bibliográficos
Autores principales: Li, Yijun, Hong, Xiumei, Liang, Liming, Wang, Xiaobin, Ladd-Acosta, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439592/
https://www.ncbi.nlm.nih.gov/pubmed/37596607
http://dx.doi.org/10.1186/s13148-023-01551-4