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Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models

BACKGROUND: Hydrocephalus is a pathological accumulation of cerebrospinal fluid (CSF), leading to ventriculomegaly. Hydrocephalus may be primary or secondary to traumatic brain injury, infection, or intracranial hemorrhage. Regardless of cause, current treatment involves surgery to drain the excess...

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Detalles Bibliográficos
Autores principales: Hochstetler, Alexandra, Smith, Hillary, Reed, Makenna, Hulme, Louise, Territo, Paul, Bedwell, Amanda, Persohn, Scott, Perrotti, Nicola, D’Antona, Lucia, Musumeci, Francesca, Schenone, Silvia, Blazer-Yost, Bonnie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439616/
https://www.ncbi.nlm.nih.gov/pubmed/37596666
http://dx.doi.org/10.1186/s12987-023-00461-0