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Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models
BACKGROUND: Hydrocephalus is a pathological accumulation of cerebrospinal fluid (CSF), leading to ventriculomegaly. Hydrocephalus may be primary or secondary to traumatic brain injury, infection, or intracranial hemorrhage. Regardless of cause, current treatment involves surgery to drain the excess...
Autores principales: | Hochstetler, Alexandra, Smith, Hillary, Reed, Makenna, Hulme, Louise, Territo, Paul, Bedwell, Amanda, Persohn, Scott, Perrotti, Nicola, D’Antona, Lucia, Musumeci, Francesca, Schenone, Silvia, Blazer-Yost, Bonnie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439616/ https://www.ncbi.nlm.nih.gov/pubmed/37596666 http://dx.doi.org/10.1186/s12987-023-00461-0 |
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