TLR7 activation by miR-21 promotes renal fibrosis by activating the pro-inflammatory signaling pathway in tubule epithelial cells

BACKGROUND: Toll-like receptor 7 (TLR7) is an endosomal TLR activated by single-stranded RNA, including endogenous microRNAs. Although TLR7 is known to promote inflammatory responses in pathophysiological conditions, its role in renal fibrosis has not been investigated. Here, we aim to investigate t...

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Detalles Bibliográficos
Autores principales: Kim, Jeongwon, Ha, Sugyeong, Son, Minjung, Kim, Doyeon, Kim, Mi-Jeong, Kim, Bumseok, Kim, Donghwan, Chung, Hae Young, Chung, Ki Wung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439664/
https://www.ncbi.nlm.nih.gov/pubmed/37596656
http://dx.doi.org/10.1186/s12964-023-01234-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439664/
https://www.ncbi.nlm.nih.gov/pubmed/37596656
http://dx.doi.org/10.1186/s12964-023-01234-w

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