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Periplasmic stress contributes to a trade-off between protein secretion and cell growth in Escherichia coli Nissle 1917

Maximizing protein secretion is an important target in the design of engineered living systems. In this paper, we characterize a trade-off between cell growth and per-cell protein secretion in the curli biofilm secretion system of Escherichia coli Nissle 1917. Initial characterization using 24-h con...

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Detalles Bibliográficos
Autores principales: Emani, Sivaram Subaya, Kan, Anton, Storms, Timothy, Bonanno, Shanna, Law, Jade, Ray, Sanhita, Joshi, Neel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439730/
https://www.ncbi.nlm.nih.gov/pubmed/37601821
http://dx.doi.org/10.1093/synbio/ysad013