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Ferroptosis and EMT: key targets for combating cancer progression and therapy resistance

Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe(2+)) and lipid peroxidation, of which are controlled by glutathione peroxidase 4 (GPX4). Its crucial role in stopping the s...

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Detalles Bibliográficos
Autores principales: Ren, Yuqing, Mao, Xiangrong, Xu, Hui, Dang, Qin, Weng, Siyuan, Zhang, Yuyuan, Chen, Shuang, Liu, Shutong, Ba, Yuhao, Zhou, Zhaokai, Han, Xinwei, Liu, Zaoqu, Zhang, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439860/
https://www.ncbi.nlm.nih.gov/pubmed/37598126
http://dx.doi.org/10.1007/s00018-023-04907-4