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Ferroptosis and EMT: key targets for combating cancer progression and therapy resistance
Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe(2+)) and lipid peroxidation, of which are controlled by glutathione peroxidase 4 (GPX4). Its crucial role in stopping the s...
Autores principales: | Ren, Yuqing, Mao, Xiangrong, Xu, Hui, Dang, Qin, Weng, Siyuan, Zhang, Yuyuan, Chen, Shuang, Liu, Shutong, Ba, Yuhao, Zhou, Zhaokai, Han, Xinwei, Liu, Zaoqu, Zhang, Guojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439860/ https://www.ncbi.nlm.nih.gov/pubmed/37598126 http://dx.doi.org/10.1007/s00018-023-04907-4 |
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