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An autophagy-inducing stapled peptide induces mitochondria dysfunction and triggers autotic cell death in triple-negative breast cancer

Autophagy is a lysosome-dependent bulk degradation process essential for cell viability but excessive autophagy leads to a unique form of cell death termed autosis. Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer with notable defect in its autophagy process. In p...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaozhe, Shan, Gao, Li, Na, Chen, Jingyi, Ji, Changyang, Li, Xiaoxiao, Jiang, Liwen, Lee, Terence Kin Wah, Keng, Vincent W., Zhao, Yanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439894/
https://www.ncbi.nlm.nih.gov/pubmed/37598181
http://dx.doi.org/10.1038/s41420-023-01600-0