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OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

The intestinal epithelium is a single cell layer that is constantly renewed and acts as a physical barrier that separates intestinal microbiota from underlying tissues. In inflammatory bowel disease (IBD) in humans, as well as in experimental mouse models of IBD, this barrier is impaired, causing mi...

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Detalles Bibliográficos
Autores principales: Verboom, Lien, Anderson, Christopher J., Jans, Maude, Petta, Ioanna, Blancke, Gillian, Martens, Arne, Sze, Mozes, Hochepied, Tino, Ravichandran, Kodi S., Vereecke, Lars, van Loo, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439912/
https://www.ncbi.nlm.nih.gov/pubmed/37598207
http://dx.doi.org/10.1038/s41419-023-06058-7