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OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
The intestinal epithelium is a single cell layer that is constantly renewed and acts as a physical barrier that separates intestinal microbiota from underlying tissues. In inflammatory bowel disease (IBD) in humans, as well as in experimental mouse models of IBD, this barrier is impaired, causing mi...
Autores principales: | Verboom, Lien, Anderson, Christopher J., Jans, Maude, Petta, Ioanna, Blancke, Gillian, Martens, Arne, Sze, Mozes, Hochepied, Tino, Ravichandran, Kodi S., Vereecke, Lars, van Loo, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439912/ https://www.ncbi.nlm.nih.gov/pubmed/37598207 http://dx.doi.org/10.1038/s41419-023-06058-7 |
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