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Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1

Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions. Transcription factor FOXM1 overexpresses in multi...

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Detalles Bibliográficos
Autores principales: Bu, Huitong, Lan, Xianling, Cheng, Haojie, Pei, Chaozhu, Ouyang, Min, Chen, Yan, Huang, Xiaoqin, Yu, Li, Tan, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439915/
https://www.ncbi.nlm.nih.gov/pubmed/37598210
http://dx.doi.org/10.1038/s41419-023-06056-9