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Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics

Histone deacetylases are important epigenetic regulators that have been reported to play essential roles in cancer stem cell functions and are promising therapeutic targets in many cancers including glioblastoma. However, the functionally relevant roles of specific histone deacetylases, in the maint...

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Detalles Bibliográficos
Autores principales: Bahia, Ravinder K., Hao, Xiaoguang, Hassam, Rozina, Cseh, Orsolya, Bozek, Danielle A., Luchman, H. Artee, Weiss, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439933/
https://www.ncbi.nlm.nih.gov/pubmed/37598220
http://dx.doi.org/10.1038/s41467-023-40776-y