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Predicting HPV association using deep learning and regular H&E stains allows granular stratification of oropharyngeal cancer patients

Human Papilloma Virus (HPV)-associated oropharyngeal squamous cell cancer (OPSCC) represents an OPSCC subgroup with an overall good prognosis with a rising incidence in Western countries. Multiple lines of evidence suggest that HPV-associated tumors are not a homogeneous tumor entity, underlining th...

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Detalles Bibliográficos
Autores principales: Klein, Sebastian, Wuerdemann, Nora, Demers, Imke, Kopp, Christopher, Quantius, Jennifer, Charpentier, Arthur, Tolkach, Yuri, Brinker, Klaus, Sharma, Shachi Jenny, George, Julie, Hess, Jochen, Stögbauer, Fabian, Lacko, Martin, Struijlaart, Marijn, van den Hout, Mari F.C.M., Wagner, Steffen, Wittekindt, Claus, Langer, Christine, Arens, Christoph, Buettner, Reinhard, Quaas, Alexander, Reinhardt, Hans Christian, Speel, Ernst-Jan, Klussmann, Jens Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439941/
https://www.ncbi.nlm.nih.gov/pubmed/37598255
http://dx.doi.org/10.1038/s41746-023-00901-z