Enantioselective organocatalytic synthesis of axially chiral aldehyde-containing styrenes via S(N)Ar reaction-guided dynamic kinetic resolution

The precise and efficient construction of axially chiral scaffolds, particularly toward the aryl-alkene atropoisomers with impeccably full enantiocontrol and highly structural diversity, remains greatly challenging. Herein, we disclose an organocatalytic asymmetric nucleophilic aromatic substitution...

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Detalles Bibliográficos
Autores principales: Guo, Fengyuan, Fang, Siqiang, He, Jiajia, Su, Zhishan, Wang, Tianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439945/
https://www.ncbi.nlm.nih.gov/pubmed/37598233
http://dx.doi.org/10.1038/s41467-023-40840-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439945/
https://www.ncbi.nlm.nih.gov/pubmed/37598233
http://dx.doi.org/10.1038/s41467-023-40840-7

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