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Enantioselective organocatalytic synthesis of axially chiral aldehyde-containing styrenes via S(N)Ar reaction-guided dynamic kinetic resolution
The precise and efficient construction of axially chiral scaffolds, particularly toward the aryl-alkene atropoisomers with impeccably full enantiocontrol and highly structural diversity, remains greatly challenging. Herein, we disclose an organocatalytic asymmetric nucleophilic aromatic substitution...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439945/ https://www.ncbi.nlm.nih.gov/pubmed/37598233 http://dx.doi.org/10.1038/s41467-023-40840-7 |