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Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models

BACKGROUND: Rhinovirus (RV) infection of airway epithelial cells triggers asthma exacerbations, during which airway smooth muscle (ASM) excessively contracts. Due to ASM contraction, airway epithelial cells become mechanically compressed. We previously reported that compressed human bronchial epithe...

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Detalles Bibliográficos
Autores principales: Dy, Alane Blythe C., Girkin, Jason, Marrocco, Antonella, Collison, Adam, Mwase, Chimwemwe, O’Sullivan, Michael J., Phung, Thien-Khoi N., Mattes, Joerg, Koziol-White, Cynthia, Gern, James E., Bochkov, Yury A., Bartlett, Nathan W., Park, Jin-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440034/
https://www.ncbi.nlm.nih.gov/pubmed/37598152
http://dx.doi.org/10.1186/s12931-023-02510-6