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Nme(2)Cas9‐mediated therapeutic editing in inhibiting angiogenesis after wet age‐related macular degeneration onset
BACKGROUND: Age‐related macular degeneration (AMD), particularly wet AMD characterised by choroidal neovascularization (CNV), is a leading cause of vision loss in the elderly. The hypoxia‐inducible factor‐1α (HIF‐1α)/vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) pathway contribu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440058/ https://www.ncbi.nlm.nih.gov/pubmed/37598400 http://dx.doi.org/10.1002/ctm2.1383 |