Nme(2)Cas9‐mediated therapeutic editing in inhibiting angiogenesis after wet age‐related macular degeneration onset

BACKGROUND: Age‐related macular degeneration (AMD), particularly wet AMD characterised by choroidal neovascularization (CNV), is a leading cause of vision loss in the elderly. The hypoxia‐inducible factor‐1α (HIF‐1α)/vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) pathway contribu...

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Detalles Bibliográficos
Autores principales: Hu, Sihui, Chen, Yuxi, Xie, Dongchun, Xu, Kan, Fu, Yunzhao, Chi, Wei, Liu, Haiying, Huang, Junjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440058/
https://www.ncbi.nlm.nih.gov/pubmed/37598400
http://dx.doi.org/10.1002/ctm2.1383

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