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Treatment of Ulcerative Colitis by Cationic Liposome Delivered NLRP3 siRNA

PURPOSE: The abnormal activation of NLRP3 inflammasome is related to the occurrence and development of ulcerative colitis (UC). However, the ideal drug and delivery system remain important factors limiting the targeting of NLRP3 inflammasome in UC therapy. Gene therapy by delivering siRNA is effecti...

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Detalles Bibliográficos
Autores principales: Huang, Jing, Dai, Mengmeng, He, Mingxia, Bu, Weicheng, Cao, Liwen, Jing, Jing, Cao, Run, Zhang, Hailong, Men, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440093/
https://www.ncbi.nlm.nih.gov/pubmed/37605735
http://dx.doi.org/10.2147/IJN.S413149