Cargando…

Treatment of Ulcerative Colitis by Cationic Liposome Delivered NLRP3 siRNA

PURPOSE: The abnormal activation of NLRP3 inflammasome is related to the occurrence and development of ulcerative colitis (UC). However, the ideal drug and delivery system remain important factors limiting the targeting of NLRP3 inflammasome in UC therapy. Gene therapy by delivering siRNA is effecti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jing, Dai, Mengmeng, He, Mingxia, Bu, Weicheng, Cao, Liwen, Jing, Jing, Cao, Run, Zhang, Hailong, Men, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440093/ https://www.ncbi.nlm.nih.gov/pubmed/37605735 http://dx.doi.org/10.2147/IJN.S413149

Ejemplares similares

Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy
por: Gladkikh, Daniil V., et al.
Publicado: (2021)

Skin Delivery of siRNA Using Sponge Spicules in Combination with Cationic Flexible Liposomes
por: Liang, XueJiao, et al.
Publicado: (2020)

Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
por: Alshehri, Abdullah, et al.
Publicado: (2018)

Retrovirus-delivered siRNA
por: Devroe, Eric, et al.
Publicado: (2002)

Publisher Correction: Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
por: Alshehri, Abdullah, et al.
Publicado: (2018)

pH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery
por: Yao, Yao, et al.
Publicado: (2015)

Cationic Liposomes Carrying siRNA: Impact of Lipid Composition on Physicochemical Properties, Cytotoxicity and Endosomal Escape
por: Lechanteur, Anna, et al.
Publicado: (2018)

Effect of Cationic Lipid Type in Folate-PEG-Modified Cationic Liposomes on Folate Receptor-Mediated siRNA Transfection in Tumor Cells
por: Hattori, Yoshiyuki, et al.
Publicado: (2019)

Efficient siRNA Delivery by the Cationic Liposome DOTAP in Human Hematopoietic Stem Cells Differentiating into Dendritic Cells
por: Martino, Sabata, et al.
Publicado: (2009)

Efficient delivery of Notch1 siRNA to SKOV3 cells by cationic cholesterol derivative-based liposome
por: Zhao, Yun-Chun, et al.
Publicado: (2016)

Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes
por: Hattori, Yoshiyuki, et al.
Publicado: (2022)

Edible and cation-free kiwi fruit derived vesicles mediated EGFR-targeted siRNA delivery to inhibit multidrug resistant lung cancer
por: Huang, Haoying, et al.
Publicado: (2023)

Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery
por: Yu, Xiaolin, et al.
Publicado: (2021)

Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes
por: Hattori, Yoshiyuki, et al.
Publicado: (2021)

Liposomal codelivery of an SN38 prodrug and a survivin siRNA for tumor therapy
por: Bi, Ye, et al.
Publicado: (2018)

Inhibition of liver fibrosis using vitamin A-coupled liposomes to deliver matrix metalloproteinase-2 siRNA in vitro
por: LI, YIPING, et al.
Publicado: (2015)

VEGF siRNA delivered by polycation liposome-encapsulated calcium phosphate nanoparticles for tumor angiogenesis inhibition in breast cancer
por: Chen, Jinliang, et al.
Publicado: (2017)

Hydrogel–metal-organic-framework hybrids mediated efficient oral delivery of siRNA for the treatment of ulcerative colitis
por: Gao, Meng, et al.
Publicado: (2022)

PD-1-siRNA delivered by attenuated Salmonella enhances the antimelanoma effect of pimozide
por: Zhao, Tiesuo, et al.
Publicado: (2019)

In Vivo GFP Knockdown by Cationic Nanogel-siRNA Polyplexes
por: Shrivats, Arun R., et al.
Publicado: (2015)

Amylose-Based Cationic Star Polymers for siRNA Delivery
por: Nishimura, Tomoki, et al.
Publicado: (2015)

Cationic Magnetite Nanoparticles for Increasing siRNA Hybridization Rates
por: Prilepskii, Artur Y., et al.
Publicado: (2020)

A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection
por: Pei, Jiawei, et al.
Publicado: (2023)

Targeting HPV‐infected cervical cancer cells with PEGylated liposomes encapsulating siRNA and the role of siRNA complexation with polyethylenimine
por: Levine, Rachel M., et al.
Publicado: (2016)

In vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis
por: Zhou, Xinyan, et al.
Publicado: (2022)

Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells
por: Constantinescu, Cristina Ana, et al.
Publicado: (2019)

Dual-modified cationic liposomes loaded with paclitaxel and survivin siRNA for targeted imaging and therapy of cancer stem cells in brain glioma
por: Sun, Xiyang, et al.
Publicado: (2018)

Efficient Treatment of Rheumatoid Arthritis by Degradable LPCE Nano-Conjugate-Delivered p65 siRNA
por: Chen, Xiaohua, et al.
Publicado: (2022)

Folate-targeted star-shaped cationic copolymer co-delivering docetaxel and MMP-9 siRNA for nasopharyngeal carcinoma therapy
por: Liu, Tao, et al.
Publicado: (2016)

Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy
por: Liu, Hong-Mei, et al.
Publicado: (2017)

Effect of the amount of cationic lipid used to complex siRNA on the cytotoxicity and proinflammatory activity of siRNA-solid lipid nanoparticles
por: Hanafy, Mahmoud S., et al.
Publicado: (2023)

Treatment of Colon Cancer by Degradable rrPPC Nano-Conjugates Delivered STAT3 siRNA
por: Zhang, Hongjia, et al.
Publicado: (2020)

Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
por: Golkar, Nasim, et al.
Publicado: (2016)

Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain
por: Kim, Taejin, et al.
Publicado: (2020)

The siRNAsome: A Cation‐Free and Versatile Nanostructure for siRNA and Drug Co‐delivery
por: Zheng, Meng, et al.
Publicado: (2019)

Chitosan-Based Glycolipid Conjugated siRNA Delivery System for Improving Radiosensitivity of Laryngocarcinoma
por: Miao, Jing, et al.
Publicado: (2021)

siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene
por: Zhang, Chunling, et al.
Publicado: (2006)

Anionic liposomes prepared without organic solvents for effective siRNA delivery
por: Han, Xiu, et al.
Publicado: (2023)

Visualization of self-delivering hydrophobically modified siRNA cellular internalization
por: Ly, Socheata, et al.
Publicado: (2017)

Co-Delivery Of Dihydroartemisinin And HMGB1 siRNA By TAT-Modified Cationic Liposomes Through The TLR4 Signaling Pathway For Treatment Of Lupus Nephritis
por: Diao, Lu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bua41qh8ni0h7e0adetvt4grn1