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Elucidation of the interaction of apocarotenoids with calf thymus DNA by biophysical techniques and in vitro study in MCF-7 cells to explore their potential in cancer therapy

OBJECTIVE(S): DNA is one of the targets of cancer-therapeutic small molecules. Cisplatin, a DNA intercalator, is one of the first-line drugs in the cancer chemo regimen which comes with health-compromising side effects during chemotherapy. The synergistic effect of natural molecules with cisplatin c...

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Detalles Bibliográficos
Autores principales: Mathew, Jill Elza, Ramamoorthy, Siva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440139/
https://www.ncbi.nlm.nih.gov/pubmed/37605726
http://dx.doi.org/10.22038/IJBMS.2023.69926.15213