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Single-cell RNA-seq and bulk-seq identify RAB17 as a potential regulator of angiogenesis by human dermal microvascular endothelial cells in diabetic foot ulcers

BACKGROUND: Angiogenesis is crucial in diabetic wound healing and is often impaired in diabetic foot ulcers (DFUs). Human dermal microvascular endothelial cells (HDMECs) are vital components in dermal angiogenesis; however, their functional and transcriptomic characteristics in DFU patients are not...

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Detalles Bibliográficos
Autores principales: Du, Hengyu, Li, Shenghong, Lu, Jinqiang, Tang, Lingzhi, Jiang, Xiao, He, Xi, Liang, Jiaji, Liao, Xuan, Cui, Taixing, Huang, Yuesheng, Liu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440157/
https://www.ncbi.nlm.nih.gov/pubmed/37605780
http://dx.doi.org/10.1093/burnst/tkad020