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Can mass drug administration of moxidectin accelerate onchocerciasis elimination in Africa?

Epidemiological and modelling studies suggest that elimination of Onchocerca volvulus transmission (EoT) throughout Africa may not be achievable with annual mass drug administration (MDA) of ivermectin alone, particularly in areas of high endemicity and vector density. Single-dose Phase II and III c...

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Detalles Bibliográficos
Autores principales: Kura, Klodeta, Milton, Philip, Hamley, Jonathan I. D., Walker, Martin, Bakajika, Didier K., Kanza, Eric M., Opoku, Nicholas O., Howard, Hayford, Nigo, Maurice M., Asare, Sampson, Olipoh, George, Attah, Simon K., Mambandu, Germain L., Kennedy, Kambale Kasonia, Kataliko, Kambale, Mumbere, Mupenzi, Halleux, Christine M., Hopkins, Adrian, Kuesel, Annette C., Kinrade, Sally, Basáñez, Maria-Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440165/
https://www.ncbi.nlm.nih.gov/pubmed/37598705
http://dx.doi.org/10.1098/rstb.2022.0277