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Stem Cell Properties of Gastric Cancer Stem-Like Cells under Stress Conditions Are Regulated via the c-Fos/UCH-L3/β-Catenin Axis

Gastric cancer stem-like cells (GCSCs) possess stem cell properties, such as self-renewal and tumorigenicity, which are known to induce high chemoresistance and metastasis. These characteristics of GCSCs are further enhanced by autophagy, worsening the prognosis of patients. Currently, the mechanism...

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Detalles Bibliográficos
Autores principales: Lee, Jae Hyeong, Park, Sang-Ah, Park, Il-Geun, Yoon, Bo Kyung, Lee, Jung-Shin, Lee, Ji Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440266/
https://www.ncbi.nlm.nih.gov/pubmed/37460253
http://dx.doi.org/10.14348/molcells.2023.0011