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OCE-205 in rats and non-human primates: Pharmacokinetic and pharmacodynamic analysis

Treatment for complications associated with the hemodynamic consequences of decompensated cirrhosis remains suboptimal. Terlipressin, the latest pharmacological management of hepatorenal syndrome–acute kidney injury (HRS-AKI), targets the vasopressin system but has serious side effects. OCE-205 is a...

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Detalles Bibliográficos
Autores principales: Bukofzer, Stan, Harris, Geoff, Cable, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440361/
https://www.ncbi.nlm.nih.gov/pubmed/37608843
http://dx.doi.org/10.1016/j.crphar.2023.100163